Name of institution: Jagiellonian Universiy, Faculty
of Chemistry
Address: Ingardena Str. 3, 30-060 Cracow,
Poland
Web site http://www.chemia.uj.edu.pl
Contact person:
Pawel KOSCIELNIAK
Professor
phone: 12 48 633 63 77, ext. 20 08
fax: 12 48 634 05 15
e-mail: koscieln@chemia.uj.edu.pl
Keywords: Flow analysis;
Flow systems; Calibration;
Research profile:
The research is focused on the problem of accuracy
of the analytical results. The objective is to develop, design, test and introduce
into analytical practice the fully automated and computerised instrumental
systems allowing the analytical procedures to be controlled and improved in
terms of accuracy.
The systems developed are based on variable flow-rate
methodology and served for on-line realisation of the analytical procedures.
The purpose covers such procedural steps as analytical calibration, dilution,
reagent additions, preconcentration etc. A sample analysed
is automatically processed according to the chemical and physicochemical
requirements and the signals measured for the sample components determined
(analytes) are transformed to the analytical information with the aid of specific chemometric methods. The results are
statistically evaluated. The systems are computerised and governed by original
software.
At present, the flow system for
calibration by so called “integrated calibration method” is developed. It
allows a single standard solution to be used for calibration and the analyte
concentration in a sample to be estimated in four independent ways. Owing
to that the estimations can be mutually verified giving a chance to determine
the analyte with improved accuracy. The system is tested in various analytical
systems and it is intended to be applied to routine analysis in near future.
Domains of applications:
All types of chemical analyses; especially such
cases when the analytical procedures are costly and laborious as well as the
samples examined are of complex matrix.